Sunday, April 27, 2008
Diagnosis of autoimmune Disease
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Welcome to the diagnosis page of CIDP on the Web. Updated Oct 21 2007
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For detailed info on diagnosis, prevention & treatment of autoimmune diseases see the , "Flame within contents".
Diagnosis of all the autoimmune diseases is simple. All the diseases present with the chief complaint of fatigue, tiredness, weakness which often comes in cycles (remits and relapses) or (waxes and wanes). Remember that if your disease comes in attacks which are days, weeks, months apart then you have autoimmune disease. All the autoimmune diseases are associated with a elevated SED rate or ESR. (Sed Rate is a simple blood test which measures inflammation). C-reactive protein (CRP) is a more sophisticated blood test which also is used to measure inflammation, CRP will also be elevated in autoimmune diseases. However my personnel experience sed rate is a better test as compared to CRP for mass screening and disease follow up.
Some Fibromyalgia patients will present with pain only on the left side of the body and in a similar way early Parkinson will only affect the left side of the body. All the diseases are immune mediated and if you follow the disease pattern you can diagnose and treat the disease on the first visit without any tests or procedures.
The human body is the most sensitive machine and I can just see and diagnose most diseases. To me it looks like the diagnosis is written on the face of the patient. I sense the disease, you can too if you try. Dont depend on diagnostic tests. Most diseases will not show up on the tests. Lets take the case of Fibromyalgia, the only test I have seen come back positive in this diseases is IgG sub class deficiency. But in reality the diagnosis can be seen as a anxious look on the patients face who is begging for a diagnosis. Feel with your fingers and feel the pain, if the patient has a headache then feel the sclap and if the scalp is tender then two things should come to mind either it is a vasculitis like Temporal arteritis or it is a case of Myofacial pain/ fibromyalgia.
CIDPUSA has published its extensive research in the autoimmune diseases E-BOOK which contains treatment of Alzheimer's, CIDP, neuropathies, Pemphigus, acne, alopecia , every type of arthritis, psychiatric disorders and many more by simple antibiotics. Save your money and purchase this book online today 24 hour delivery to your email. Check this offer on our home page. Hundreds of satisfied patients worldwide. Remember this is true research by university doctors and not the research that you see in the news supported by Big Pharma.
In CIDP, patients usually present with a history of weakness, numbness, pain and difficulty in walking. Some patients may have a sudden onset of back pain or neck pain radiating down the extremities. This pain is usually diagnosed as radicular pain (radiating pain or going down). The symptoms of CIDP are usually progressive and may come and go. The patients have difficulty climbing stairs and use their hands to pull themselves upstairs.
On examination the patients may have weakness in hips and shoulders, loss of deep tendon reflexes (rarely increased or normal).
There may be atrophy (shrinkage) of muscles, fasciculations (twitching) and loss of sensation in the feet and hands.
Some patients present with ALS (Lugaric Disease) like clinical picture. Who have MMF (Multi-Focal Motor neuropathy. As these patients have no sensory loss, but just weakness.
The patients may present with a single cranial nerve or peripheral nerve dysfunction. For example, double vision, loss of hearing, ringing in the ear, face dropping on one side, hoarseness, facial pain. They can have weak hand grip, numbness in the hands or feet. Pain in the neck or back .
They may present with abdominal pains, fainting spells while standing up. Burning pain in extremities.
Laboratory findings
The major laboratory tests for CIDP are electrophysiologic studies, CSF examination, and nerve biopsy.
Electrophysiological Tests consist of two parts.
EMG or Electro-Myo-Graphy is a test where a electrical needle is placed in a muscle to record its electrical activity. It is used to differentiate other causes of muscle weakness, such as myopathy (inflammation of muscle), axonal neuropathies (Dysfunction in the center of the nerve) and disorders of neuromuscular transmission (dysfunction at the place where a nerve connects to a muscle) seen in Myasthenia.
NCV is a Nerve-conduction-Velocity is the second part of the Electrophysiological Test. In NCV a nerve is shocked by a electrical current and the time this current takes to reach a second point is measured. If the speed of this measured electrical conduction is slow, then the nerve conduction studies show demyelination or CIDP. If the speed is slightly slow then a axonal neuropathy is considered which may be due to vitamin deficiency.
Some of the NCV findings include:
(a) a slowing in the nerve conduction velocities ; (meaning that the Myelin around a nerve is damaged or rarely the axon is affected)
(b) the presence of conduction block or abnormal temporal dispersion in at least one motor nerve (meaning no or little electrical current is transmitted in the nerve). Is seen in Mutli Focal Motor Neuropathy.
(c) prolonged distal latencies in at least two nerves;(means that it takes a long time for the current to get past the ends of the shocked nerve) This portion is a good way to measure for carpal tunnel syndrome. At CIDPUSA we believe CTS is due to the inflammation of a nerve and does not need surgery.
(d) absent F waves or prolonged minimum F wave latencies in at least two motor nerves. Means that a F wave is not seen in these patients. This F wave is a stimulation of the nerve in the opposite direction, towards the spin and the distance from the spine back to the nerve is measured. F wave will be absent in Diabetic Amyotrophy or swelling of the spinal discs causing inflammation on the nerve.
(In some case EMG/NCV can be normal). EMG does not tell what is the cause of your disease, it can only locate the site of the damage.
CSF Examination: Cerebro Spinal Fuid is the fluid that bathes your brain and spinal cord. Cytoalbuminologic dissociation (means elevated CSF protein >45 in the absence of a high cell count <10) is characteristic of CIDP & GBS. CSF pleocytosis is rare except in HIV-associated CIDP. An elevated IgG index and IgG synthesis rate is consistent with the immune-related nature of CIDP.
Imran Khan MBBS Nanotech Neurology Lahore
Not all the patients will have lab abnormalities. In many the EMG/NCV findings will not show that they have CIDP yet they will still have the disease.
Is EMG/NCV Insensitive in the Diagnosis of CIDP?
The clinical profile of chronic inflammatory demyelinating polyneuropathy (CIDP) is variable. Nerve conduction studies are essential for the diagnosis of CIDP; however, current electrophysiologic criteria for CIDP may not be sensitive. These authors analyzed results of nerve conduction studies and nerve biopsies in 8 patients with CIDP who did not fulfill standard electrophysiologic criteria (of 44 patients with CIDP confirmed by nerve histology). Two standard electrophysiologic criteria were used: one proposed by an ad hoc committee of the AAN (Neurology 1991; 41:617) and another by the Inflammatory Neuropathy Cause and Treatment Group (Ann Neurol 2001; 50:195).
The main electrophysiologic abnormalities were those of simple axonopathy in 7 patients; the other patient had almost normal electrophysiologic results. In contrast, examination of nerve biopsies in all 8 patients revealed substantial loss of myelinated fibers; in addition, frequent histologic findings were naked axons, thinly myelinated fibers, and various degrees of onion bulbs. These histology findings were identical to those of the 36 other CIDP patients. The authors conclude that many patients with unrecognized CIDP are erroneously classified by electrodiagnosis as having chronic axonal neuropathy and that nerve biopsy should be considered to further investigate a chronic idiopathic neuropathy.
Click to view different size nerve fibers.
: Neurology. 2002 Dec 24;59(12 Suppl 6):S2-6.
Diagnosis of CIDP. Latov N. Peripheral Neuropathy Center, Weill Medical College of Cornell University, New York, NY 10022, USA.Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease that targets the myelin sheaths of peripheral nerves. In clinical practice the diagnosis is often difficult to make because of the clinical heterogeneity of the disease, its multifocality and predilection for proximal nerve segments, and the limitations of our electrophysiologic and pathologic techniques. Although there are rather stringent research criteria for selecting patients to clinical trials, there are no generally agreed-on clinical diagnostic criteria for CIDP, and application of the research criteria to routine clinical practice would miss the diagnosis in a majority of patients. Because of this uncertainty, the prevalence of CIDP is greatly underestimated, and patients are often left untreated despite progression of their disease. However, given what is known about the clinical presentation and pathophysiology of CIDP, patients with neuropathy of otherwise unknown etiology are more likely to have CIDP than idiopathic axonal neuropathy, and warrant a trial of therapy if they have nerve conduction velocities below the lower limits of normal, prolongation of F-waves beyond the normal range, or presence of conduction block or temporal dispersion. A favorable response to therapy, consisting of stabilization or improvement of the neuropathy, would confirm the diagnosis
The human cervical plexus or nerves coming out of the neck into the arms.
www.cidpusa.org www.cidpusa.org/P/ivig.htm http://www.cidpusa.org/disease.html
autoimmune E-Book
PURCHASE autoimmune diseases E-BOOK
Autoimmune diseases are the number one killer among men, women and animals. The number one cause of disease is autoimmune. Learn to prevent these diseases before they start. Simple treatments to stop them. Complete management with diet alone for athletes Myocarditis to Alzheimer's. Take your health in your hands do not wait for surprises.
The book is aimed as a guide for people to learn how to diagnose, treat and avoid autoimmune diseases. We addresses the cause of these diseases, Alzheimer's, heart disease, stroke, which can be stopped in their tracks. All treatments are from published studies and reports from universities around the world. A quick guide for doctors, nurses, patients and medical students. Drug doses, side effects, treatment protocols. Total pages 197.
THE MOST COSTLY DISEASE TO TREAT ARE AUTOIMMUNE DISEASES. This book will help you save more then $2000- $ 30,000 a year in Medical cost.
This is a E-book or electronic book which will only be sent to you by E-MAIL. In adobe acrobat format. (We will not mail any printed copies). Pay Pal transaction will cause a 6-12 hour delay till you get a download link delivered to your email. For any delay contact PayPal and also contact.
Dr Imran Khan
Buy at holiday sale price for only 12.99 This is a electronic book , If you are in the vicinity of Lahore call us and arrange a local pickup in word or pdf format. You will recover the money you spend to buy the book in the first month. (20 years of research in 200 pages)
-----------------------------------------------------------------------------------------
Written in a easy to understand plain English style. (Bulk purchases for Medical Schools, Insurance companies and Health Plans available please contact)
Buy at holiday sale price for only 12.99 This is a electronic book
Autoimmune Inflammatory disorders (The Flame Within)
Prevention, Risk Factors, Diagnosis, Medical and Alternative Treatments.
Preface
This book is addressed to solve the personal, social and medical challenges facing the individuals, implications to the individuals suffering from the difficult to diagnose conditions are provided. Thousands of individuals with Chronic Fatigue and Fibromyalgia, Multiple Sclerosis, neuropathy and epilepsy can improve with immunomodulatory treatments.
Autoimmune diseases have become the number one diseases process today. Currently heart disease, diabetes, cancers, strokes are all fueled by autoimmune mechanisms. By a mechanism called molecular mimicry which is the basis of all of autoimmune diseases; a deceived immune system starts to attacks its own body cells, which it was supposed to protect. Centers of disease control and American Heart Association recently issued a joint statement asking doctors to check for inflammatory disease in patients with stroke and heart disease!
Treatment of autoimmune diseases should be directed at the cause. We present our case against pathogens responsible for deceiving our immune system and causing autoimmune disease. Removing the causative organism has ended the era of deception, thousands of individuals have improved and couple of hundred reports have been published confirming what you will find in this book.
Majority of the diseases are triggered by know pathogens, gliadin a glycoprotein in gluten causes Celiac disease. It is necessary to remove these proteins to achieve a cure from autoimmune diseases they cause. We have included treatment guidelines which range from over the counter diet products to expensive infusions. Guidelines for treatment of Alzheimer's, arthritis, heart attacks, Fibromyalgia and Chronic Fatigue are provided. These protocols will stop the disease process in its tracks!
Even the diagnosis of autoimmune disease has been simplified by observation of the disease cycle. Simple tests to confirm inflammatory disease and associated immune deficiency are provided. We hope to revolutionize the treatment of autoimmune diseases, by illuminating a step by step process to diagnose and treat the molecular basis.
Autoimmune conditions keep on growing daily so those diseases not addressed will be included in the upcoming edition." A quick guide for doctors, nurses, patients and medical students. Drug doses, side effects, treatment protocols. These up-to-date protocols are not being taught in medical schools. A must for every physician. Total pages 197
Upon reading the first five chapters you will be able to diagnose any future autoimmune disease. We will have new diseases presenting every year get ready today.
Thanks
Dr. Imran Khan MBBS (Bachelor of Medicine and Bachelor of Surgery) Board Certified Neurology and Psychiatry (USA) Nanotech Medical Center Lahore.
Trained at the Royal Postgraduate Medical School London, Institute of neurology Queens Square London, National Institutes of Health Bethesda Maryland and University of Arizona. Was appointed to the United States Public Health Service as a Lt. Commander by the President of the USA. Served in the office of the Surgeon General USA and at National Institutes of Health Bethesda MD.
Twenty years of research has shown that simple antibiotics are helping cure chronic fatigue, arthritis, Fibromyalgia, PTSD, ALS and Alzheimer's. Discover these wonder drugs in this book.
Contents
Glossary: page 6
Chapter 1 Introduction to Inflammation 9
The Attack on Self Tissues: 12
Stages of autoimmune disease 13
Chapter 2 Causative factors in autoimmune disease 13
Genetic Factors
Diet
Sunshine
Vaccination 15
Injury
Stress
Excessive Exercise
Chemicals 16
Poisoning 18
Pharmaceutical triggers
Infections
Immune reconstitution inflammatory syndrome (IRIS) 19
Chapter 3 Diagnosis of Autoimmune Disease 20
Symptoms of autoimmune disease
Simple Blood tests for autoimmune disease 22
Antibody tests
Chapter 4 Diet for prevention of autoimmune diseases 23
Magnesium, Zinc, Aluminum, Fluoride
Gluten free diet 25
Organic foods, Vitamin 26
Fluids, Soda, Beer 28
Breathing, Exercise, Smoking
Clothing, Hygiene
Spirituality 30
Fasting 31
Spices 33
Chapter 5 The Immune system
Innate Immunity: 35
Adaptive Immunity:
Passive Immunity:
Heat shock proteins (HSP), 36
The Immune System Disorders.
Chapter 6 Neurological Autoimmune Diseases
Acute disseminated encephalomyelitis (ADEM) 36
Autoimmune Epilepsy syndromes
Landau-Kleffner syndrome (LKS) 38
Lennox-Gastaut syndrome
Infantile spasm (IS) or West Syndrome 40
Absence epilepsy, 41
Epilepsia Partialis Continua (E.P.C)
Rasmussen's Encephalitis, & Parry-Romberg syndrome
Tests for autoimmune epilepsy 42
Autoimmune Epilepsy treatment
Alzheimer's treatment (Memory problems) 45
Myelopathy – NeuroMyelitis Optica – Transverse Myelitis 47
CIDP & autoimmune neuropathies 49
Lewis-Sumner syndrome 50
Multifocal Motor Neuropathy 51
ANTI-MAG (Myelin Associated Glycoprotein) Neuropathy
MGUS Monoclonal gammopathy of unknown significance 52
Small Fiber Neuropathy, Sensory CIDP, DADSN
Diagnosis of CIDP 53
Blood tests for neuropathy, nerve-biopsy, lab-tests cidp, 54
CIDP treatment Protocol 55
Immune treatments CIDP 56
List-A drugs for autoimmune diseases 58
Prognosis of neuropathy 60
CIDP in Children
Guillain-Barre Syndrome 60
Miller Fisher Syndrome
autoimmune neuropathies,Leprosy 62
Tabes Dorsalis
Facial Palsy 63
Dystonia Hemifacial Spasma & Blephrospasm, 64
Diabetic neuropathy,amyotrophy 64
Autonomic small-fiber Neuropathy 65
Holmes-Adie syndrome: (HAS) Ross syndrome & Harlequin syndrome 66
Reflex sympathetic dystrophy 67
Palatal myoclonus
Trigeminal Neuralgia 68
Autoimmune ALS: 69
Chronic Lyme disease 70
Multiple Sclerosis 71
Lambert-Eaton Syndrome 73
Myasthenia Gravis 74
Stiff-Person Syndrome 77
Sydenham chorea 78
Parkinsons with an autoimmune etiology 79
Paraneoplastic neurological Syndromes 80
(Autonomic dysfunction, Brainstem encephalitis,
Cerebellar degeneration, Focal cortical encephalitis,
Lambert Eaton Myasthenic Syndrome, Limbic encephalitis,
Anxiety, Myelitis, Opsoclonus/myoclonus,
Retinopathy & Sensory neuropathy)
NeuroMyotonia: Isaac's syndrome, 82
Moyamoya disease
Migraine in autoimmune diseases 83
Cluster headache in autoimmune diseases 85
Autoimmune disc herniation and Sciatica 85
Narcolepsy 86
Central pontine myelinolysis 87
Stroke & Transient Ischemic Attacks 87
Chapter 7 Cardiovascular Autoimmune Diseases
Kawasaki Disease 88
Autoimmune Myocarditis 89
Rheumatic Autoimmune Myocarditis: 90
Lymes Myocarditis 92
Autoimmune Viral Myocarditis 93
Influenza Myocarditis history:
Giant cell Myocarditis (GCM) The most fatal Disease 94
Autoimmune Myocarditis in Athletes
Autoimmune Atherosclerosis 95
Chapter 8 Ophthalmic Autoimmune Diseases 98
Double Vision
Sympathetic opthalmitis 100
Optic Neuritis Loss of vision
Orbital Myositis 101
Chapter 9 Skin & Hair Autoimmune Diseases
Autoimmune Urticaria 102
Alopecia Areata Hair Loss 103
Autoimmune Atopic Dermatitis or Eczema 105
Vitiligo white spots on skin 105
Pemphigus vulgaris (PV) skin peels off 106
Pemphigus Foliaceus
Bullous Pemphigoid (BP) 107
Cicatricial Pemphigoid
Lichen planus 109
Rosacea red face and nose 110
Livedoid vasculopathy 111
Chapter 10 Rheumatic Autoimmune Diseases
Rheumatoid arthritis 112
Ankylosing Spondylitis (AS) Bamboo spine 114
Scleroderma Tight skin
Osteoarthritis (OA) 115
Psoriasis 116
Reactive Arthritis and Reiter's Syndrome 117
Scleroderma CREST 118
Autoimmune Vasculitis
Giant Cell Arteritis Old woman with headaches 120
Takayasu arteritis (two week treatment) pulsless disease 121
Behcet's Disease oral vaginal ulcers 122
Churg-Strauss Syndrome (CSS) 123
Wegeners
Sjogren's dry mouth and vagina
Dermatomyositis & Polymyositis weak shoulders 125
SLE or Lupus 127
Antiphospholipid syndrome recurrent abortion 128
Mixed Connective Tissue Disease or overlap disorders
Fibromyalgia Womens disease pain all over and fatigue 131
Chronic Fatigue Syndrome / Gulf war syndrome tired all the time 132
MCTD & UCTD trigeminal neuralgia , face pain + SLE 133
Chapter 11 Psychiatric Autoimmune Diseases
Autism not so normal child 134
P.A.N.D.A.S or O.C.D repetitive handwashing 137
Autoimmune Neuropsychiatric disorders & Depression 138
P.T.S.D. stress that causes recurrent dreams & thoughts about that event 140
Chapter 12 Autoimmune Gastro Intestinal Diseases
Celiac disease allergy to Gluten 141
Autoimmune pancreatitis (AIP) 141
Crohns disease Mucus in stool and pain 143
Ulcerative Colitis 144
Autoimmune Gastritis (AIG) 146
Duodenal ulcer autoimmune 148
Autoimmune acalculous cholecystitis 149
Autoimmune Hepatitis 149
Chapter 13 Autoimmune Hemolytic & Lymphoproliferative Diseases
Lymphoproliferative Syndrome 151
Autoimmune Hemophilia 152
The autoimmune hemolytic anemias
Iron deficiency anemia 153
I.T.P. (Autoimmune Thrombocytopenia) 155
Lymphoma & autoimmune diseases 156
Cryoglobulinemia 157
Porphyria 158
Chapter 14 Autoimmune inner ear disease 160
Menieres Disease
Sudden Autoimmune Deafness, Vertigo, & Tinnitus
Vogt-Koyanagi-Harada syndrome 161
Chapter 15 Autoimmune Endocrine disease.
Sheehan's syndrome, empty sella syndrome, 161
relapsing remitting lymphocytic hypophysitis.
Diabetes Insipidus
Hashimotos Thyroiditis 163
Graves Disease
Diabetes insipidus 165
Diabetes mellitus
Addison disease 168
Chapter 16 Autoimmune Gynecological / Obstetrics diseases.
Autoimmune Endometriosis 169
Recurrent Spontaneous Abortion 170
Male Infertility
Eclampsia. 171
Chronic Pelvic pain 172
Chapter 17 Respiratory autoimmune Disorders
Asthma 173
Sarcoidosis 174
Amyloidosis 175
Interstitial lung disease 178
(ILD, Bronchiolitis obliterans and organizing pneumonia (BOOP).
Diffuse alveolar damage (DAD)
adult respiratory distress syndrome (ARDS)
Chapter 18 Renal autoimmune Disorders
Interstitial cystitis 180
Henoch-Schonlein purpura. 181
Glomerulonephritis Autoimmune Kidney failure 181
Chronic Autoimmune Prostatitis (CAP), Nonbacterial Prostatitis,
Chronic Pelvic Pain Syndrome
Wegener's granulomatosis involving the urogenital tract 183
(Orchitis-ureteral stenosis-pseudotumor)
Chapter 19 what is IVIG (Intravenous Immunoglobulin) 184
Chapter 20 Pain stiffness 187
Chapter 21 Managed Care, disability 189
Chapter 22 Mold, MSG, Mad Cow 190
Chapter 23 Joint replacement, implants & Chlamydia 192
Acknowledgements
Buy at holiday sale price for only 12.99 This is a electronic book
Welcome to the CIDP International organization
Electronic book for download only no hardcopy.
After reading this book you will learn how to fix the the root cause of the disease. You can offer your patients a cure on day 1 without waiting for lab tests. We train doctors to become autoimmune experts and offer a fellowship in autoimmune diseases ask for our one day course.
Statements on this page not evaluated by FDA.
Autoimmune diseases are the number one killer among men, women and animals. The number one cause of disease is autoimmune. Learn to prevent these diseases before they start. Simple treatments to stop them. Complete management with diet alone for athletes Myocarditis to Alzheimer's. Take your health in your hands do not wait for surprises.
The book is aimed as a guide for people to learn how to diagnose, treat and avoid autoimmune diseases. We addresses the cause of these diseases, Alzheimer's, heart disease, stroke, which can be stopped in their tracks. All treatments are from published studies and reports from universities around the world. A quick guide for doctors, nurses, patients and medical students. Drug doses, side effects, treatment protocols. Total pages 197.
THE MOST COSTLY DISEASE TO TREAT ARE AUTOIMMUNE DISEASES. This book will help you save more then $2000- $ 30,000 a year in Medical cost.
This is a E-book or electronic book which will only be sent to you by E-MAIL. In adobe acrobat format. (We will not mail any printed copies). Pay Pal transaction will cause a 6-12 hour delay till you get a download link delivered to your email. For any delay contact PayPal and also contact.
Dr Imran Khan
Buy at holiday sale price for only 12.99 This is a electronic book , If you are in the vicinity of Lahore call us and arrange a local pickup in word or pdf format. You will recover the money you spend to buy the book in the first month. (20 years of research in 200 pages)
-----------------------------------------------------------------------------------------
Written in a easy to understand plain English style. (Bulk purchases for Medical Schools, Insurance companies and Health Plans available please contact)
Buy at holiday sale price for only 12.99 This is a electronic book
Autoimmune Inflammatory disorders (The Flame Within)
Prevention, Risk Factors, Diagnosis, Medical and Alternative Treatments.
Preface
This book is addressed to solve the personal, social and medical challenges facing the individuals, implications to the individuals suffering from the difficult to diagnose conditions are provided. Thousands of individuals with Chronic Fatigue and Fibromyalgia, Multiple Sclerosis, neuropathy and epilepsy can improve with immunomodulatory treatments.
Autoimmune diseases have become the number one diseases process today. Currently heart disease, diabetes, cancers, strokes are all fueled by autoimmune mechanisms. By a mechanism called molecular mimicry which is the basis of all of autoimmune diseases; a deceived immune system starts to attacks its own body cells, which it was supposed to protect. Centers of disease control and American Heart Association recently issued a joint statement asking doctors to check for inflammatory disease in patients with stroke and heart disease!
Treatment of autoimmune diseases should be directed at the cause. We present our case against pathogens responsible for deceiving our immune system and causing autoimmune disease. Removing the causative organism has ended the era of deception, thousands of individuals have improved and couple of hundred reports have been published confirming what you will find in this book.
Majority of the diseases are triggered by know pathogens, gliadin a glycoprotein in gluten causes Celiac disease. It is necessary to remove these proteins to achieve a cure from autoimmune diseases they cause. We have included treatment guidelines which range from over the counter diet products to expensive infusions. Guidelines for treatment of Alzheimer's, arthritis, heart attacks, Fibromyalgia and Chronic Fatigue are provided. These protocols will stop the disease process in its tracks!
Even the diagnosis of autoimmune disease has been simplified by observation of the disease cycle. Simple tests to confirm inflammatory disease and associated immune deficiency are provided. We hope to revolutionize the treatment of autoimmune diseases, by illuminating a step by step process to diagnose and treat the molecular basis.
Autoimmune conditions keep on growing daily so those diseases not addressed will be included in the upcoming edition." A quick guide for doctors, nurses, patients and medical students. Drug doses, side effects, treatment protocols. These up-to-date protocols are not being taught in medical schools. A must for every physician. Total pages 197
Upon reading the first five chapters you will be able to diagnose any future autoimmune disease. We will have new diseases presenting every year get ready today.
Thanks
Dr. Imran Khan MBBS (Bachelor of Medicine and Bachelor of Surgery) Board Certified Neurology and Psychiatry (USA) Nanotech Medical Center Lahore.
Trained at the Royal Postgraduate Medical School London, Institute of neurology Queens Square London, National Institutes of Health Bethesda Maryland and University of Arizona. Was appointed to the United States Public Health Service as a Lt. Commander by the President of the USA. Served in the office of the Surgeon General USA and at National Institutes of Health Bethesda MD.
Twenty years of research has shown that simple antibiotics are helping cure chronic fatigue, arthritis, Fibromyalgia, PTSD, ALS and Alzheimer's. Discover these wonder drugs in this book.
Contents
Glossary: page 6
Chapter 1 Introduction to Inflammation 9
The Attack on Self Tissues: 12
Stages of autoimmune disease 13
Chapter 2 Causative factors in autoimmune disease 13
Genetic Factors
Diet
Sunshine
Vaccination 15
Injury
Stress
Excessive Exercise
Chemicals 16
Poisoning 18
Pharmaceutical triggers
Infections
Immune reconstitution inflammatory syndrome (IRIS) 19
Chapter 3 Diagnosis of Autoimmune Disease 20
Symptoms of autoimmune disease
Simple Blood tests for autoimmune disease 22
Antibody tests
Chapter 4 Diet for prevention of autoimmune diseases 23
Magnesium, Zinc, Aluminum, Fluoride
Gluten free diet 25
Organic foods, Vitamin 26
Fluids, Soda, Beer 28
Breathing, Exercise, Smoking
Clothing, Hygiene
Spirituality 30
Fasting 31
Spices 33
Chapter 5 The Immune system
Innate Immunity: 35
Adaptive Immunity:
Passive Immunity:
Heat shock proteins (HSP), 36
The Immune System Disorders.
Chapter 6 Neurological Autoimmune Diseases
Acute disseminated encephalomyelitis (ADEM) 36
Autoimmune Epilepsy syndromes
Landau-Kleffner syndrome (LKS) 38
Lennox-Gastaut syndrome
Infantile spasm (IS) or West Syndrome 40
Absence epilepsy, 41
Epilepsia Partialis Continua (E.P.C)
Rasmussen's Encephalitis, & Parry-Romberg syndrome
Tests for autoimmune epilepsy 42
Autoimmune Epilepsy treatment
Alzheimer's treatment (Memory problems) 45
Myelopathy – NeuroMyelitis Optica – Transverse Myelitis 47
CIDP & autoimmune neuropathies 49
Lewis-Sumner syndrome 50
Multifocal Motor Neuropathy 51
ANTI-MAG (Myelin Associated Glycoprotein) Neuropathy
MGUS Monoclonal gammopathy of unknown significance 52
Small Fiber Neuropathy, Sensory CIDP, DADSN
Diagnosis of CIDP 53
Blood tests for neuropathy, nerve-biopsy, lab-tests cidp, 54
CIDP treatment Protocol 55
Immune treatments CIDP 56
List-A drugs for autoimmune diseases 58
Prognosis of neuropathy 60
CIDP in Children
Guillain-Barre Syndrome 60
Miller Fisher Syndrome
autoimmune neuropathies,Leprosy 62
Tabes Dorsalis
Facial Palsy 63
Dystonia Hemifacial Spasma & Blephrospasm, 64
Diabetic neuropathy,amyotrophy 64
Autonomic small-fiber Neuropathy 65
Holmes-Adie syndrome: (HAS) Ross syndrome & Harlequin syndrome 66
Reflex sympathetic dystrophy 67
Palatal myoclonus
Trigeminal Neuralgia 68
Autoimmune ALS: 69
Chronic Lyme disease 70
Multiple Sclerosis 71
Lambert-Eaton Syndrome 73
Myasthenia Gravis 74
Stiff-Person Syndrome 77
Sydenham chorea 78
Parkinsons with an autoimmune etiology 79
Paraneoplastic neurological Syndromes 80
(Autonomic dysfunction, Brainstem encephalitis,
Cerebellar degeneration, Focal cortical encephalitis,
Lambert Eaton Myasthenic Syndrome, Limbic encephalitis,
Anxiety, Myelitis, Opsoclonus/myoclonus,
Retinopathy & Sensory neuropathy)
NeuroMyotonia: Isaac's syndrome, 82
Moyamoya disease
Migraine in autoimmune diseases 83
Cluster headache in autoimmune diseases 85
Autoimmune disc herniation and Sciatica 85
Narcolepsy 86
Central pontine myelinolysis 87
Stroke & Transient Ischemic Attacks 87
Chapter 7 Cardiovascular Autoimmune Diseases
Kawasaki Disease 88
Autoimmune Myocarditis 89
Rheumatic Autoimmune Myocarditis: 90
Lymes Myocarditis 92
Autoimmune Viral Myocarditis 93
Influenza Myocarditis history:
Giant cell Myocarditis (GCM) The most fatal Disease 94
Autoimmune Myocarditis in Athletes
Autoimmune Atherosclerosis 95
Chapter 8 Ophthalmic Autoimmune Diseases 98
Double Vision
Sympathetic opthalmitis 100
Optic Neuritis Loss of vision
Orbital Myositis 101
Chapter 9 Skin & Hair Autoimmune Diseases
Autoimmune Urticaria 102
Alopecia Areata Hair Loss 103
Autoimmune Atopic Dermatitis or Eczema 105
Vitiligo white spots on skin 105
Pemphigus vulgaris (PV) skin peels off 106
Pemphigus Foliaceus
Bullous Pemphigoid (BP) 107
Cicatricial Pemphigoid
Lichen planus 109
Rosacea red face and nose 110
Livedoid vasculopathy 111
Chapter 10 Rheumatic Autoimmune Diseases
Rheumatoid arthritis 112
Ankylosing Spondylitis (AS) Bamboo spine 114
Scleroderma Tight skin
Osteoarthritis (OA) 115
Psoriasis 116
Reactive Arthritis and Reiter's Syndrome 117
Scleroderma CREST 118
Autoimmune Vasculitis
Giant Cell Arteritis Old woman with headaches 120
Takayasu arteritis (two week treatment) pulsless disease 121
Behcet's Disease oral vaginal ulcers 122
Churg-Strauss Syndrome (CSS) 123
Wegeners
Sjogren's dry mouth and vagina
Dermatomyositis & Polymyositis weak shoulders 125
SLE or Lupus 127
Antiphospholipid syndrome recurrent abortion 128
Mixed Connective Tissue Disease or overlap disorders
Fibromyalgia Womens disease pain all over and fatigue 131
Chronic Fatigue Syndrome / Gulf war syndrome tired all the time 132
MCTD & UCTD trigeminal neuralgia , face pain + SLE 133
Chapter 11 Psychiatric Autoimmune Diseases
Autism not so normal child 134
P.A.N.D.A.S or O.C.D repetitive handwashing 137
Autoimmune Neuropsychiatric disorders & Depression 138
P.T.S.D. stress that causes recurrent dreams & thoughts about that event 140
Chapter 12 Autoimmune Gastro Intestinal Diseases
Celiac disease allergy to Gluten 141
Autoimmune pancreatitis (AIP) 141
Crohns disease Mucus in stool and pain 143
Ulcerative Colitis 144
Autoimmune Gastritis (AIG) 146
Duodenal ulcer autoimmune 148
Autoimmune acalculous cholecystitis 149
Autoimmune Hepatitis 149
Chapter 13 Autoimmune Hemolytic & Lymphoproliferative Diseases
Lymphoproliferative Syndrome 151
Autoimmune Hemophilia 152
The autoimmune hemolytic anemias
Iron deficiency anemia 153
I.T.P. (Autoimmune Thrombocytopenia) 155
Lymphoma & autoimmune diseases 156
Cryoglobulinemia 157
Porphyria 158
Chapter 14 Autoimmune inner ear disease 160
Menieres Disease
Sudden Autoimmune Deafness, Vertigo, & Tinnitus
Vogt-Koyanagi-Harada syndrome 161
Chapter 15 Autoimmune Endocrine disease.
Sheehan's syndrome, empty sella syndrome, 161
relapsing remitting lymphocytic hypophysitis.
Diabetes Insipidus
Hashimotos Thyroiditis 163
Graves Disease
Diabetes insipidus 165
Diabetes mellitus
Addison disease 168
Chapter 16 Autoimmune Gynecological / Obstetrics diseases.
Autoimmune Endometriosis 169
Recurrent Spontaneous Abortion 170
Male Infertility
Eclampsia. 171
Chronic Pelvic pain 172
Chapter 17 Respiratory autoimmune Disorders
Asthma 173
Sarcoidosis 174
Amyloidosis 175
Interstitial lung disease 178
(ILD, Bronchiolitis obliterans and organizing pneumonia (BOOP).
Diffuse alveolar damage (DAD)
adult respiratory distress syndrome (ARDS)
Chapter 18 Renal autoimmune Disorders
Interstitial cystitis 180
Henoch-Schonlein purpura. 181
Glomerulonephritis Autoimmune Kidney failure 181
Chronic Autoimmune Prostatitis (CAP), Nonbacterial Prostatitis,
Chronic Pelvic Pain Syndrome
Wegener's granulomatosis involving the urogenital tract 183
(Orchitis-ureteral stenosis-pseudotumor)
Chapter 19 what is IVIG (Intravenous Immunoglobulin) 184
Chapter 20 Pain stiffness 187
Chapter 21 Managed Care, disability 189
Chapter 22 Mold, MSG, Mad Cow 190
Chapter 23 Joint replacement, implants & Chlamydia 192
Acknowledgements
Buy at holiday sale price for only 12.99 This is a electronic book
Welcome to the CIDP International organization
Electronic book for download only no hardcopy.
After reading this book you will learn how to fix the the root cause of the disease. You can offer your patients a cure on day 1 without waiting for lab tests. We train doctors to become autoimmune experts and offer a fellowship in autoimmune diseases ask for our one day course.
Statements on this page not evaluated by FDA.
Vision: Early diagnosis & cure of autoimmune disease. Mission: To cure autoimmune disease.
Pork plant controversy explained CIDP is a group of 101 autoimmune diseases affecting the brain, hearing, vision, taste, spinal cord, muscles & nerves. Read & learn.
Read Autoimmune diseases are the number one disease process and killer on Planet Earth. In autoimmune diseases our own white cells start attacking the body organs. The attack is triggered by infections, surgery, accidents, inhalation of pollutants and stress. A two week specific anti-inflammatory treatment can stop these diseases & alter their course. Arthritis, stiffness, pain mental disorders, heart problems, skin diseases, facial palsy, asthma, hearing disorders, multiple sclerosis are all autoimmune.
A gene in the British Royal Family triggers autoimmune diseases.
If a disease has good & bad days, or it is progressive, consider it to be a autoimmune disorder. If the disease started after pregnancy, surgery, car accidents, toxic exposure or living close to a dump, its autoimmune. Don't wait, the sooner you treat the better the results. After the termination of pregnancy a increased autoimmune attack is seen & autoimmune diseases are triggered after pregnancy including Vasculitis, depression & PTSD.
P.T.S.D. (post traumatic stress disorder), depression, anxiety, O.C.D (obsessive compulsive disorder), heart disease, bowel, kidney, breathing and skin disorders, memory loss & epilepsy are all immune mediated. Sudden onset of hearing loss, visual disorders & infertility are all immune mediated. Get quick answers in our e-book. It helps change the way you live, joint pains relived, memory improves, sleep is better.
Arthritis, vasculitis, Alzheimer's, Lupus, Asthma, Chronic Pain, Prostatis, Chronic Fatigue, Fibromyalgia , hair loss, hair falling out are all treatable. Hair have grown in completely bald men with simple medication & supplements.
Young women with undiagnosed problems please read about Dysautonomia in section three on this page.
Autoimmune diseases can start after food poisoning, vaccination, chemical exposure, injury, severe exercise, exposure to mold and minor stretching of unused muscles. Those people who eat less nuts have more autoimmune diseases. In women chronic pains and autoimmune diseases usually starts after a cesarean section or hysterectomy. Do not think that hot flashes are due to hormone deficiency. Treatment of any disease by thinking that immune dysfunction is the cause.
President Franklin D Roosevelt (click to see his medical history) President J.F. Kennedy (medical history)
Below is a description of a common autoimmune nerve disorder, for other diseases please see our disease section. or E-Book.
Tingling numbness in the toes can be Chronic Inflammatory Demyelinating Polyneuropathy . Diabetics have a higher incidence of CIDP. A super expert medical professional can diagnose CIDP on the first visit without any electro-diagnostic help, read our diagnosis page to find out which is the best test.
Any polyneuropathy is more likely to be CIDP. Chronic inflammatory demyelinating polyradiculo neuropathy is an immune-mediated Polyneuropathy (inflammatory) that affects the nerves. The symptoms are a slowly progressive, numbness and tingling starts in the feet, and then involves legs and hands. Sufferer notices weakness in the legs, later in the arms. Some complain of inability to walk or maintain balance in the dark. There is frequently some spinal cord involvement. Occasionally, cranial nerves are involved, symptoms range from visual perception difficulties, double vision, numbness involving the face, hearing disorders. Cognitive skills are not affected by CIDP. Most people believe that their knee, ankles or hip joints are a problem. Muscle and spinal involvement is frequent in CIDP. Brain involvement in CIDP is misdiagnosed as MS.
A CIDP patient uses the hands to go upstairs or rise from the squatting position, these are signs of legs becoming weaker. Some have difficulty to maintain their blood pressure, burning sensations like, (Reflex Sympathetic Dystrophy. Complex regional pain syndrome) are more likely to be CIDP. Diabetic neuropathy is more likely to be CIDP. The spinal tap may show a rise in the protein level of the spinal fluid. Electromyography with nerve conduction studies may show slowing of EMG/NCV. This nerve study will be normal when the small fibers (autonomic nerves) are involved. Autonomic involvement cause feelings of (Pain and burning). The course of CIDP is remitting relapsing, it gets better and then worse again. Rarely the attacks come once a month, or couple of months apart." Dr King Engle speaking at CIDPUSA meeting said a normal EMG/NCV does not rule out CIDP.
CIDP is misdiagnosed as ALS. Due to a mix of upper and lower motor neuron lesions (brain, spinal-cord + peripheral nerve). M.M.F. (Multifocal Motor Neuropathy) also looks like ALS has no sensory involvement. Autoimmune ALS will have sensory changes and I call this a CIDP variant. Thus a false diagnose of ALS can be made. Dr King Engle in Los Angles has helped such patients who came in wheelchairs and in two months were walking. Untreated CIDP can turn into ALS. (ALS is a CIDP spectrum disorder)
Current standards to diagnose CIDP do not recommend a nerve biopsy: As the skip lesions of CIDP may or may not be seen in Sural nerve biopsy. After biopsy the patient may have a sensory deficit. Which may be worse then the original disease. I have seen people who are worse off due to nerve biopsy. Dr. Katz in San Francisco has said that Leprosy may be the only reason to do a nerve biopsy.
Finding of inflammation in the nerve biopsy, is rare, definitely will confirm the diagnosis of CIDP. However, the absence of inflammation does not rule out CIDP. Findings of demyelination (loss of myelin around the nerve) on the nerve biopsy can be used to confirm the clinical presentation and suggest a diagnosis of CIDP. I find the nerve biopsy unnecessary.
For those in whom this procedure has to be done. The best technique is described by a Austrian team. Where they only remove a 10mm piece of the Sural nerve and reattach the stumps by microsurgical repair. They claim none of their patients had any complaints of pain or sensory loss.
However Massachusetts General Hospital has come off with a novel idea of doing a skin biopsy instead of a nerve biopsy. This provides more information in small fiber neuropathies and is less invasive. In the old days GBS patients were in bed for 6 months, today patients improve in a few days, due to modern treatments.
According to Dr. Jonathan Katz the best test for CIDP is to give treatment and see if the patient responds to the treatment. (This saves time and money.) Howard W. Sander, MD and Norman Latov, MD PhD have said , "although patients may not meet the diagnostic criteria for inclusion in clinical trials of CIDP, they may still benefit from current and future treatments used in CIDP". So doctors, Please, Don't follow guidelines of ANA!
I have used intra muscular & subcutaneous IVIG injections to reverse CIDP in three days with a much lower IVIG dose. I prefer to use antibiotics mentioned in the e-book to reverse CIDP.
Our E-book has the complete step by step protocol, for diagnosis of all the seven sub types of CIDP and 101 autoimmune diseases. Their treatment, and alternative supplements which helps people get back on their feet. These protocols covers Alzheimers, CIDP, MS, Pemphigus, just to name a few!
For long term treatment, (interferon, Cellcept, Cyclosporine, Cyclophosphamide, Methotrexate are used ) These drugs suppress the immune system. Severe immune suppression can lead to other problems (cancer). IVIg and Cyclosporine combination is described successfully in several reports. Steroids are only used for short term benefits. Some Centers are using Avonex, Enbrel, Remicade and Rituxan. From early reports all of these drugs works well, recently a novel pharmaceutical has been seen to help CIDP! These cheap drugs help many autoimmune diseases. (answer in our e-book).
CIDP responds to prednisone the side effects of this medication have to be considered for long term use. Oral prednisone takes about 30 days to show an effect reported by Dr. Jonathan Katz. Intravenous pulse steroids reach the efficacy of IVIg.
Can CIDP be cured? Yes, without IVIg I have cured CIDP many times. The first report of CIDP cure was reported after a tonsillectomy, currently the Government (NIH) is investigating if stem cell transplant will cure CIDP. Jennifer who is the first stem cell transplant patient in USA is described in story number three..
Post Polio syndrome benefits from CIDP treatments, as they actually have CIDP. Currently there are case reports that IVIg has even helped patients with C.M.T disease, lumbar and brachial neuritis (weak thighs and weak arms cannot comb your hair or cannot get out of a chair), transverse Myelitis (both the legs are weak & stiff). Diabetic Amyotrophy (weak legs in a diabetic) is considered to be a vasculitis (inflammation) and is responsive to immune treatments as reported in ten different studies.
(C.M.T. or Charcot Marie Tooth disease, the legs look like inverted wine bottles or stork legs)
The Greatest doctor of all times Hippocrates said, the human body should be treated as a whole and not in parts, as is being routinely done. The CIDP autoimmune clinic works on the Hippocratic principal. We offer treatment to help the whole body.
Narcotics & antidepressants are not the best way to treat CIDP or autoimmune patients. Avicenna (Ibn Cenna), in his encyclopedia of medicine wrote, "it is best for the patient that the cause of their disease be treated". Narcotics cause immune suppression. Any sick patient will be depressed, one needs to treat the disease not the symptoms. Once the disease is treated, then depression and pain will go away. In postpartum PTSD & depression treat the inflammation rather then give a serotonin reuptake inhibitor.
Help yourself and read the diet section. We are all suffering due to pollution and a poor diet. We need to detoxify. All the above info is taken from research literature available at the National Library of Medicine in Washington DC.
If you have a autoimmune disorder then avoid Vaccination! If you have IgG sub-class deficiency (frequent allergies, infections & fatigue) then stay away from tetanus and flu shots. Do not vaccinate or give vaccination drops to sick children.
We have sold our e-book on nearly every continent of the world to satisfied readers. This detailed discussion on CIDP is not found in any textbook or web site. CIDPUSA provide similar discussion for every disease in the e-book called, "the flame within". We aim to cure diseases, a two year progressive transverse myelitis cured in three days read the story in our Nanotechnology page. (story 25)
Dr Imran Khan Board Certified Neurology Psychiatry USA, Medical Director, Nanotech Medical & Neurology Center 56 E-2 WAPDA Town, Lahore -Pakistan tele: 0322-4569778
Dr Khan served in the United States Public Health Service, appointed by the President of the United States. Promoted by the Surgeon General of USA to a Lt. Commander in the USPS. Served in the United States Civil Service as a Research Fellow at the National Institutes of Health, Bethesda. Residency Neurology at University of Arizona, Royal Postgraduate Medical School London and Institute of Neurology Queens Square London. This website designed by Dr Khan a certified network engineer by Cisco Systems.
Pork plant controversy explained CIDP is a group of 101 autoimmune diseases affecting the brain, hearing, vision, taste, spinal cord, muscles & nerves. Read & learn.
Read Autoimmune diseases are the number one disease process and killer on Planet Earth. In autoimmune diseases our own white cells start attacking the body organs. The attack is triggered by infections, surgery, accidents, inhalation of pollutants and stress. A two week specific anti-inflammatory treatment can stop these diseases & alter their course. Arthritis, stiffness, pain mental disorders, heart problems, skin diseases, facial palsy, asthma, hearing disorders, multiple sclerosis are all autoimmune.
A gene in the British Royal Family triggers autoimmune diseases.
If a disease has good & bad days, or it is progressive, consider it to be a autoimmune disorder. If the disease started after pregnancy, surgery, car accidents, toxic exposure or living close to a dump, its autoimmune. Don't wait, the sooner you treat the better the results. After the termination of pregnancy a increased autoimmune attack is seen & autoimmune diseases are triggered after pregnancy including Vasculitis, depression & PTSD.
P.T.S.D. (post traumatic stress disorder), depression, anxiety, O.C.D (obsessive compulsive disorder), heart disease, bowel, kidney, breathing and skin disorders, memory loss & epilepsy are all immune mediated. Sudden onset of hearing loss, visual disorders & infertility are all immune mediated. Get quick answers in our e-book. It helps change the way you live, joint pains relived, memory improves, sleep is better.
Arthritis, vasculitis, Alzheimer's, Lupus, Asthma, Chronic Pain, Prostatis, Chronic Fatigue, Fibromyalgia , hair loss, hair falling out are all treatable. Hair have grown in completely bald men with simple medication & supplements.
Young women with undiagnosed problems please read about Dysautonomia in section three on this page.
Autoimmune diseases can start after food poisoning, vaccination, chemical exposure, injury, severe exercise, exposure to mold and minor stretching of unused muscles. Those people who eat less nuts have more autoimmune diseases. In women chronic pains and autoimmune diseases usually starts after a cesarean section or hysterectomy. Do not think that hot flashes are due to hormone deficiency. Treatment of any disease by thinking that immune dysfunction is the cause.
President Franklin D Roosevelt (click to see his medical history) President J.F. Kennedy (medical history)
Below is a description of a common autoimmune nerve disorder, for other diseases please see our disease section. or E-Book.
Tingling numbness in the toes can be Chronic Inflammatory Demyelinating Polyneuropathy . Diabetics have a higher incidence of CIDP. A super expert medical professional can diagnose CIDP on the first visit without any electro-diagnostic help, read our diagnosis page to find out which is the best test.
Any polyneuropathy is more likely to be CIDP. Chronic inflammatory demyelinating polyradiculo neuropathy is an immune-mediated Polyneuropathy (inflammatory) that affects the nerves. The symptoms are a slowly progressive, numbness and tingling starts in the feet, and then involves legs and hands. Sufferer notices weakness in the legs, later in the arms. Some complain of inability to walk or maintain balance in the dark. There is frequently some spinal cord involvement. Occasionally, cranial nerves are involved, symptoms range from visual perception difficulties, double vision, numbness involving the face, hearing disorders. Cognitive skills are not affected by CIDP. Most people believe that their knee, ankles or hip joints are a problem. Muscle and spinal involvement is frequent in CIDP. Brain involvement in CIDP is misdiagnosed as MS.
A CIDP patient uses the hands to go upstairs or rise from the squatting position, these are signs of legs becoming weaker. Some have difficulty to maintain their blood pressure, burning sensations like, (Reflex Sympathetic Dystrophy. Complex regional pain syndrome) are more likely to be CIDP. Diabetic neuropathy is more likely to be CIDP. The spinal tap may show a rise in the protein level of the spinal fluid. Electromyography with nerve conduction studies may show slowing of EMG/NCV. This nerve study will be normal when the small fibers (autonomic nerves) are involved. Autonomic involvement cause feelings of (Pain and burning). The course of CIDP is remitting relapsing, it gets better and then worse again. Rarely the attacks come once a month, or couple of months apart." Dr King Engle speaking at CIDPUSA meeting said a normal EMG/NCV does not rule out CIDP.
CIDP is misdiagnosed as ALS. Due to a mix of upper and lower motor neuron lesions (brain, spinal-cord + peripheral nerve). M.M.F. (Multifocal Motor Neuropathy) also looks like ALS has no sensory involvement. Autoimmune ALS will have sensory changes and I call this a CIDP variant. Thus a false diagnose of ALS can be made. Dr King Engle in Los Angles has helped such patients who came in wheelchairs and in two months were walking. Untreated CIDP can turn into ALS. (ALS is a CIDP spectrum disorder)
Current standards to diagnose CIDP do not recommend a nerve biopsy: As the skip lesions of CIDP may or may not be seen in Sural nerve biopsy. After biopsy the patient may have a sensory deficit. Which may be worse then the original disease. I have seen people who are worse off due to nerve biopsy. Dr. Katz in San Francisco has said that Leprosy may be the only reason to do a nerve biopsy.
Finding of inflammation in the nerve biopsy, is rare, definitely will confirm the diagnosis of CIDP. However, the absence of inflammation does not rule out CIDP. Findings of demyelination (loss of myelin around the nerve) on the nerve biopsy can be used to confirm the clinical presentation and suggest a diagnosis of CIDP. I find the nerve biopsy unnecessary.
For those in whom this procedure has to be done. The best technique is described by a Austrian team. Where they only remove a 10mm piece of the Sural nerve and reattach the stumps by microsurgical repair. They claim none of their patients had any complaints of pain or sensory loss.
However Massachusetts General Hospital has come off with a novel idea of doing a skin biopsy instead of a nerve biopsy. This provides more information in small fiber neuropathies and is less invasive. In the old days GBS patients were in bed for 6 months, today patients improve in a few days, due to modern treatments.
According to Dr. Jonathan Katz the best test for CIDP is to give treatment and see if the patient responds to the treatment. (This saves time and money.) Howard W. Sander, MD and Norman Latov, MD PhD have said , "although patients may not meet the diagnostic criteria for inclusion in clinical trials of CIDP, they may still benefit from current and future treatments used in CIDP". So doctors, Please, Don't follow guidelines of ANA!
I have used intra muscular & subcutaneous IVIG injections to reverse CIDP in three days with a much lower IVIG dose. I prefer to use antibiotics mentioned in the e-book to reverse CIDP.
Our E-book has the complete step by step protocol, for diagnosis of all the seven sub types of CIDP and 101 autoimmune diseases. Their treatment, and alternative supplements which helps people get back on their feet. These protocols covers Alzheimers, CIDP, MS, Pemphigus, just to name a few!
For long term treatment, (interferon, Cellcept, Cyclosporine, Cyclophosphamide, Methotrexate are used ) These drugs suppress the immune system. Severe immune suppression can lead to other problems (cancer). IVIg and Cyclosporine combination is described successfully in several reports. Steroids are only used for short term benefits. Some Centers are using Avonex, Enbrel, Remicade and Rituxan. From early reports all of these drugs works well, recently a novel pharmaceutical has been seen to help CIDP! These cheap drugs help many autoimmune diseases. (answer in our e-book).
CIDP responds to prednisone the side effects of this medication have to be considered for long term use. Oral prednisone takes about 30 days to show an effect reported by Dr. Jonathan Katz. Intravenous pulse steroids reach the efficacy of IVIg.
Can CIDP be cured? Yes, without IVIg I have cured CIDP many times. The first report of CIDP cure was reported after a tonsillectomy, currently the Government (NIH) is investigating if stem cell transplant will cure CIDP. Jennifer who is the first stem cell transplant patient in USA is described in story number three..
Post Polio syndrome benefits from CIDP treatments, as they actually have CIDP. Currently there are case reports that IVIg has even helped patients with C.M.T disease, lumbar and brachial neuritis (weak thighs and weak arms cannot comb your hair or cannot get out of a chair), transverse Myelitis (both the legs are weak & stiff). Diabetic Amyotrophy (weak legs in a diabetic) is considered to be a vasculitis (inflammation) and is responsive to immune treatments as reported in ten different studies.
(C.M.T. or Charcot Marie Tooth disease, the legs look like inverted wine bottles or stork legs)
The Greatest doctor of all times Hippocrates said, the human body should be treated as a whole and not in parts, as is being routinely done. The CIDP autoimmune clinic works on the Hippocratic principal. We offer treatment to help the whole body.
Narcotics & antidepressants are not the best way to treat CIDP or autoimmune patients. Avicenna (Ibn Cenna), in his encyclopedia of medicine wrote, "it is best for the patient that the cause of their disease be treated". Narcotics cause immune suppression. Any sick patient will be depressed, one needs to treat the disease not the symptoms. Once the disease is treated, then depression and pain will go away. In postpartum PTSD & depression treat the inflammation rather then give a serotonin reuptake inhibitor.
Help yourself and read the diet section. We are all suffering due to pollution and a poor diet. We need to detoxify. All the above info is taken from research literature available at the National Library of Medicine in Washington DC.
If you have a autoimmune disorder then avoid Vaccination! If you have IgG sub-class deficiency (frequent allergies, infections & fatigue) then stay away from tetanus and flu shots. Do not vaccinate or give vaccination drops to sick children.
We have sold our e-book on nearly every continent of the world to satisfied readers. This detailed discussion on CIDP is not found in any textbook or web site. CIDPUSA provide similar discussion for every disease in the e-book called, "the flame within". We aim to cure diseases, a two year progressive transverse myelitis cured in three days read the story in our Nanotechnology page. (story 25)
Dr Imran Khan Board Certified Neurology Psychiatry USA, Medical Director, Nanotech Medical & Neurology Center 56 E-2 WAPDA Town, Lahore -Pakistan tele: 0322-4569778
Dr Khan served in the United States Public Health Service, appointed by the President of the United States. Promoted by the Surgeon General of USA to a Lt. Commander in the USPS. Served in the United States Civil Service as a Research Fellow at the National Institutes of Health, Bethesda. Residency Neurology at University of Arizona, Royal Postgraduate Medical School London and Institute of Neurology Queens Square London. This website designed by Dr Khan a certified network engineer by Cisco Systems.
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